Secondary hyperparathyroidism in dialysis patients
Conditions
Interventions
Group 1:polycinnamalol parathyroid sclerotherapy
Group 2:Surgical total parathyroidectomy and forearm transplantation
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) All patients were older than 18 years old, both male and female; (2) All patients were dialysis patients, who underwent peritoneal dialysis or hemodialysis for more than 6 months; (3) All patients complicated with secondary hyperparathyroidism were treated conservatively for 3-6 months, but PTH > 800 pg/L; (4) Before treatment, B-mode ultrasonography or CT examination showed that parathyroid gland enlargement (volume > 500 mm3 or length > 1 cm) was present; (5) Abnormal bone metabolism (blood calcium > 2.5 mmol/L, blood phosphorus > 1.8 mmol/l, ectopic calcification).
Exclusion criteria
Exclusion criteria: 1. The presence of ectopic parathyroid glands was indicated by imaging or radionuclide scanning; 2. Patients with malignant tumors; 3. Pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum calcium;serum phosphorus;intact PTH;Bone-specific alkaline phosphatase;FGF-23; | — |
Secondary
| Measure | Time frame |
|---|---|
| Abdominal aortic calcification score; | — |
Countries
China
Contacts
Public ContactQijun Wan
Shenzhen Second People's Hospital
Outcome results
None listed