Safety and efficacy of aspirin-clopidogrel in acute non-cardiogenic minor ischemic stroke (NIHSS score <= 5): a prospective and multicenter study based on real-world

Conditions

Acute non-cardiogenic Minor Ischemic Stroke

Liu T, Wang Y, Zhang K, Fan H, Li X, Wu X, Niu X.

2025-05-16

10.1016/j.jtha.2025.04.034

Intensive Versus Moderate Statin‐Based Therapies in Patients With Mild Ischemic Stroke: A Prospective Multicenter Cohort Study

Haimei Fan, Yongle Wang, Kaili Zhang, Ting‐ting Liu, Xinyi Li et al. (20 authors)

Journal of the American Heart Association2024-07-099 citations

10.1161/jaha.124.035337

Minor stroke patients with mild-moderate diastolic blood pressure derive greater benefit from dual antiplatelet therapy

Tingting Liu, Yongle Wang, Yanan Li, Kaili Zhang, Haimei Fan et al. (20 authors)

Hypertension Research2023-09-051 citations

10.1038/s41440-023-01422-8

Dual Versus Mono Antiplatelet Therapy in Patients with Acute Mild-to-Moderate Stroke: A Multicentre Perspective Cohort Study.

Zhang K, Liu T, Fan H, Wang Y, Li Y, Li J, Li Y, Yu Y, Wang J, Xue L, Du W, Niu W, Yan Y, Gao X, Li G, Liu Q, Liu Y, Fan Y, Ren J, Li X, Wu X, Niu X.

2023-06-133 citations

10.1007/s10557-023-07468-7

Triglyceride-glucose index, symptomatic intracranial artery stenosis and recurrence risk in minor stroke patients with hypertension.

Wang Y, Liu T, Li Y, Zhang K, Fan H, Ren J, Li J, Li Y, Li X, Wu X, Wang J, Xue L, Gao X, Yan Y, Li G, Liu Q, Niu W, Du W, Liu Y, Niu X.

2023-04-1922 citations

10.1186/s12933-023-01823-6

Interventions

Aspirin:Nil

Aspirin-Clopidogrel:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Acute ischemic stroke (diagnosed according to the AHA/ASA criteria) within 72 hours of symptom onset; 2. NIHSS score 5 but raid remission or fluctuation.

Exclusion criteria

Exclusion criteria: 1. mRs>2; 2. Cardiogenic Minor Ischemic Stroke; 3. TIA; 4. Intracranial hemorrhagic disease; 5. With severe cardiopulmonary disease, the researchers think it is un- suitable to participate in this study; 6. Patients with a life expectancy of < 3 months and unable to complete the study; 7. Patients who receive early intravenous thrombolysis or who plan to receive endovascular treatment; 8. Refuse to sign informed consent.

Design outcomes

Primary

Measure	Time frame
ischemic stroke;hemorrhage stroke;TIA;myocardial infarction;vascular death;	—

Secondary

Measure	Time frame
ischemic stroke;hemorrhage stroke;TIA;	—

Countries

China

Contacts

Public ContactTingting Liu

The First Hospital of Shanxi Medical University

liutin_2000@126.com+86 13546716109

Outcome results

None listed