A study for the relationship between sufentanil dosage and cough during induction of general anesthesia

Recommended dose of sufentanil during induction of general anesthesia to avoid coughing and drastic fluctuation of hemodynamics in patients undergoing surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025149

Enrollment

Unknown

Registered

2019-08-14

Start date

2019-08-15

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sufentanil-induced cough

Interventions

A: 0.1ug/kg

B:0.3ug/kg

C:0.5ug/kg

D:1.0ug/kg

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Women; 2) ASA I or II; 3) Aged 22-65 years; 4) BMI 19-24 kg/m2.

Exclusion criteria

Exclusion criteria: 1) Patients with severe cardiovascular diseases; 2) Patients with respiratory diseases, such as chronic bronchitis, asthma and respiratory tract infection in the past two weeks; 3) Long-term use of steroids or bronchodilators and ACEI drugs; 4) Patients with neurological and psychiatric diseases; 5) Patients with hepatorenal insufficiency.

Design outcomes

Primary

Measure	Time frame
Cough frequency;	—

Countries

China

Contacts

Public ContactGong Yuan

Yichang Central People's Hospital

gy-yc@163.com+86 13986746821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026