Postoperative cognitive dysfunction
Conditions
Interventions
Sponsors
Shanghai Pudong Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 60 years and over; received hip joint replacement surgery; informed consent; ASA I or II.
Exclusion criteria
Exclusion criteria: History of psychiatric disorders, cerebrovascular diseases and diabetes; long term use of nervous and mental system drugs (such as sedative hypnotics and antidepressants); history of alcohol abuse; severe impairment on speaking, hearing and vision that difficult to communicate; MMSE score < 23 one day before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Simple Mental State Scale Score;the level of SOD in plasma;the level of MDA in plasma; | — |
Secondary
| Measure | Time frame |
|---|---|
| the level of S100ß in plasma;the level of IL-6 in plasma;the level of MMP-9 in plasma; | — |
Countries
China
Contacts
Public ContactLong Sun, zhang Nannan
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai Pudong Hospital
Outcome results
None listed