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Determination of the minimum local anaesthetic dose (MLAD) of ropivacaine in real-time ultrasound guided spinal anesthesia for lower limb surgery

Determination of the minimum local anaesthetic dose (MLAD) of ropivacaine in real-time ultrasound guided spinal anesthesia for lower limb surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025102
Enrollment
Unknown
Registered
2019-08-11
Start date
2019-08-11
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower limb disease

Interventions

Group 1:0.75% ropivacaine
Group 2:0.5% ropivacaine

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. ASA grades 1-3; 3. Lower extremity surgery; 4. Written informed consent was obtained from all participants.

Exclusion criteria

Exclusion criteria: 1. Those with contraindication of spinal anesthesia; 2. Obesity (BMI>35 kg/m2); 3. Those with history of spine surgery; 4. Those who had any infection at the proposed puncture site; 5. Those who had clotting disorders; 6. Those with history of allergy to local anesthetics.

Design outcomes

Primary

MeasureTime frame
The time when the sensory block reaches T10;Sensory block was higher than T10 plane time and the highest plane;Motor block reaches “effective” time and maintains time;Changes of BP, HR and SPO2 before and after spinal anaesthesia;Postoperative VAS scores for rest and exercise;spinal anaesthesia - related complications;Postoperative complications;

Countries

China

Contacts

Public ContactXiaochun Zheng

Department of Anesthesiology, Fujian Provincial Hospital

zhengxiaochun7766@163.com+86 13705058351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026