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Neutrophil extracellular traps formation and elimination in respiratory airway——new exploration of mechanisms for neutrophilic asthma

Neutrophil extracellular traps formation and elimination in respiratory airway——new exploration of mechanisms for neutrophilic asthma

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025092
Enrollment
Unknown
Registered
2019-08-10
Start date
2019-08-09
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Interventions

Neutrophil asthma group:none
Non-neutrophil asthma group:none
health group:none

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18 to 70 years; 2) Confirmed asthma diagnosis with positive result of bronchial provocation or dilation test; 3) Stable disease with no changes in disease condition or maintenance therapy in the 4 weeks preceding screening; 4) Able to provide informed written consent.

Exclusion criteria

Exclusion criteria: 1) Pregnancy or breast feeding; 2)Respiratory disease other than asthma or other system diseases such as pulmonary fibrosis, bronchiectasis, uncontrolled severe hypertension or heart disease and etc. 3) Ever received heart, lung, or thoracic surgeries; 4) Can not cooperate with the lung function test, sputum induction and laboratory tests.

Design outcomes

Primary

MeasureTime frame
NETs DNA;

Countries

China

Contacts

Public ContactWang Lei

West China Hospital of Sichuan University

906097972@qq.com+86 18980602097

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026