IDDS implantation for advanced cancer pain patients
Conditions
Interventions
dexmedetomidine combined with fentanyl group:Fentanyl was injected 1 µg/kg 5min before surgery,patients were intravenously pumped with dexmedetomidine 0.5 µg/kg within 10min prior to surgery and conti
Propofol combined with fentanyl group:Fentanyl was injected 1 µg/kg 5min before surgery,within 10min before the operation, the patient was intravenously pumped with 2mg/kg propofol. After the operatio
Fentanyl group:Fentanyl was injected 1 µg/kg 5min before surgery
Sponsors
Jiangsu Provincial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Aged 18 years or more, ASA II or III level. Patients with primary abdominal tumors with poor analgesic effect of oral opioids (mesecontin >=300 mg/d, VAS resting >= 5 and >3 times/day) or who cannot tolerate side effects of large doses of opioids.
Exclusion criteria
Exclusion criteria: Serious heart and lung disease, severe bradycardia, poor control of high blood pressure, unstable angina, II degree atrioventricular block, subarachnoid puncture taboo, to right the microphones, fat emulsion and other allergies, can not tolerate surgery or unfinished, unwilling to cooperate with researchers and so on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;Ramsay; | — |
Countries
China
Contacts
Public ContactSun Xiaodi
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed