Duchenne muscular dystrophy
Conditions
Interventions
Non-resistance active exercise training group:Active anti-gravity muscle strength training
Low intensity resistance exercise training group:Low intensity resistance muscle strength training
Medium intensity resistance exercise training group:Medium intensity resistance muscle strength training
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
Male
Age
5 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1. Male patients with the age of 5 to 10 years old, who can walk more than 10 meters independently and continuously. 2. The clinical symptoms, signs and laboratory results of the patients were in accordance with the diagnostic criteria of DMD. 3. The diagnosis of the patients should be established by either DNA testing or muscle biopsy, or both. 4. The patients have been receiving regular drug treatment and achieved stable effect. 5. The patients have not received regular muscle strength training intervention before.
Exclusion criteria
Exclusion criteria: 1. The patients have received surgery recently. 2. The patients have some other diseases which can affect their ability of activity. 3. The patients have cardiomyopathy with clinical symptoms. 4. The patients have the disturbance of understanding, and are unable to cooperate with the assessment and training. 5. The patients are unable to cooperate with the follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| muscle strength;ranges of motion;6-min walk test;timed function test;Motor Function Measure for Neuromuscular disorders;North Star Ambulatory Assessment;Vignos classification for lower limb function;Brooke classification for upper limb function; | — |
Countries
China
Contacts
Public ContactWenzhu Li
Peking University First Hospital
Outcome results
None listed