Population Pharmacokinetics of Valproic Acid in Patients with Bipolar Disorder and its Application in Individualized Dosage Regimen

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900025061

Enrollment

Unknown

Registered

2019-08-09

Start date

2019-09-01

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biplar Dsorder

Interventions

1: valproic acid

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients in hospital. 2. Patients who meet DSM-V for bipolar disorder. 3. Aged > 18 years. 4. All patients or their caregivers are informed, and give consent to take part in the study.

Exclusion criteria

Exclusion criteria: 1. Current or past history of serious medical illness, for example diabetes, thyroid disease, cardiovascular diseases, etc. 2. History of epilepsy, except febrile convulsion. 3. Patients who cannnot take the medication as prescribed. 4. Pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
Blood concentration of valproic acid;	—

Countries

China

Contacts

Public ContactYannan Zang

Beijing Anding Hospital, Capital Medical University

zangyannan1990@163.com+86 010 58303263

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026