Observation of cases with biorhythm phase coupled transcranial magnetic stimulation

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900025025

Enrollment

Unknown

Registered

2019-08-08

Start date

2019-08-15

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Interventions

1:Biorhythm phase coupled transcranial magnetic stimulation

2:Transcranial magnetic stimulation

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age range: 50-75 years; (2) It meets the diagnostic criteria for AD set by the National institute on aging -AD institute (NIA-AA) in 2011; (3) MMSE <= 23?; (4) CDR:1-2; (5) HAMD < 17; (6) Hachinski< 4; (7) According to the Edinburgh bias test, all are right-handed; (8) Long-term follow-up was agreed and accompanied by qualified informed persons at each follow-up.

Exclusion criteria

Exclusion criteria: (1) Complicated with other neurological diseases and serious diseases of heart, liver, lung and kidney; (2) There are metallic foreign body in the body, such as pacemaker, DBS treatment device, bracket; (3) Those who take benzodiazepines or have a history of drug abuse; (4) Patients with MDD and other severe mental illness.

Design outcomes

Primary

Measure	Time frame
Neuropsychological scale;	—

Secondary

Measure	Time frame
FMRI;TMS-EEG;	—

Countries

China

Contacts

Public ContactWang yuping

Xuanwu Hospital Capital Medical University

wangyuping01@sina.cn+86 010-83198273

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026