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A prospective randomized trial comparing cementing the apical and terminal pedicle screw and cement injections on all segments for lumbar degenerative diseases

A prospective randomized trial comparing cementing the apical and terminal pedicle screw and cement injections on all segments for lumbar degenerative diseases

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900025022
Enrollment
Unknown
Registered
2019-08-07
Start date
2019-09-02
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar degenerative diseases

Interventions

Sponsors

Spinal Surgery, the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. diagnosed with lumbar degenerative diseases, including lumbar spondylolisthesis, lumbar spinal stenosis, degenerative scoliosis, spinal instability; 2. patients suffered from severe low back pain and/or lower limb pain before operation and were ineffective after regular conservative treatment for more than three months. 3. patients with lumbar vertebral bone mineral density (BMD) measured by dual-energy X-ray absorptiometry and T <= -2.5 SD. 4. patients with posterior interbody fusion and using consecutive 2-level (fusion segment:L2-L4, L3-L5 or L4-S1) or 3-level (fusion segment: L2-L5 or L3-S1) pedicle screw implanting.

Exclusion criteria

Exclusion criteria: 1. patients with vertebral fracture, tumor or infection; 2. patients with lumbar surgery history; 3. allergy to bone cement ; 4. serious medical diseases or intolerance to operation.

Design outcomes

Primary

MeasureTime frame
screw loosening rate;fusion rate;cement leakage rate;

Countries

China

Contacts

Public ContactShuncong Zhang

The First Affiliated Hospital of Guangzhou University of Chinese Medicine

970599532@qq.com+86 13602765101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026