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Study for the mechanism of improving postoperative depression in breast cancer patients with low-dose ketamine

Study for the mechanism of improving postoperative depression in breast cancer patients with low-dose ketamine

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900025006
Enrollment
Unknown
Registered
2019-08-06
Start date
2017-05-26
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer Depression

Interventions

K1:1%ketamine
K2:0.5%ketamine
K3:0.1%ketamine
NS:0.9%NS

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Breast cancer patients undergoing elective surgery; 2. ASA I - II grade, aged 18 to 65 years old; 3. BMI - 25% ~ + 25% to breast cancer radical mastectomy (total mastectomy; total mastectomy + axillary lymph node dissection; Radical mastectomy + breast reconstruction).

Exclusion criteria

Exclusion criteria: Severe hypertension, coronary heart disease, cardiac dysfunction, pulmonary hypertension, neuropsychiatric history or drug abuse history; other mental neurological dysfunction.

Design outcomes

Primary

MeasureTime frame
Beck Depression Inventory BDI;—

Secondary

MeasureTime frame
IL-1 beta;IL-6;Tumor Necrosis Factor-alpha, TNF-alpha;—

Countries

China

Contacts

Public ContactHe Guannan

The First Hospital of China Medical University

329206429@qq.com+86 13898839613

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026