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Study of Cochlear Synaptopathy and Temporal, Frequency and Loudness Resolution of Frequency Range Limited Hidden Hearing Loss

Study of Cochlear Synaptopathy and Temporal, Frequency and Loudness Resolution of Frequency Range Limited Hidden Hearing Loss

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024995
Enrollment
Unknown
Registered
2019-08-06
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cochlear Synaptopathy and Hidden Hearing Loss

Interventions

Noise exposure hearing normal population:N/A
Hearing function normal population without history of noise exposure:N/A

Sponsors

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
23 Years to No maximum

Inclusion criteria

Inclusion criteria: (1)Exposure Group Aged 23 to 40 years; No ear disease history; Otoscope examine to check the external auditory canal and tympanic membrane for both ears are all right. Type A tympanogram for both ears. Hearing threshold 500, 1000,2000,3000,4000,6000,8000 Hz less than or equal to 25 dB HL. Working noise exposure more than or equal to 8h>80 dB(A) LAeq every working day. Working hour 8 hours, 5 days per week. Working years more than or equal to 5 years. (2) Control Group Aged 23 to 40 years; No ear disease history; Otoscope examine to check the external auditory canal and tympanic membrane for both ears are all right. Type A tympanogram for both ears. Hearing threshold 500, 1000,2000,3000,4000,6000,8000 Hz less than or equal to 25 dB HL. None occupational or damaged noise exposure history. Entertainment noise acceptation < 20 hr per week. No shooting hobby, No working noise exposure history.

Exclusion criteria

Exclusion criteria: Unable to finish the psychophysics and electrophysiology tests.

Design outcomes

Primary

MeasureTime frame
Speech perception in noise;

Secondary

MeasureTime frame
SP/AP;Gap Threshold;Temporal Modulation Transfer Function ;

Countries

China

Contacts

Public ContactLi Bei

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University, School of Medicine

libei9th2017@163.com+86 13818337502

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026