dysmenorrhea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged > 20 years; 2. The menstrual cycle is 25 to 38 days, and the total dysmenorrhea index is more than 3 points in the baseline measurement or empirical score (the sum of the two sub-scores describing the severity of dysmenorrhea and the use of painkillers). 3. If the patient has a history of smoking and smokes more than 15 cigarettes a day, the age should be less than 35 years old. 4. Clinical symptoms of dysmenorrhea:lower abdominal pain before, during or after menstrual period, radioactive pain in back or thigh, accompanied by nausea, vomiting, headache, fatigue, dizziness, diarrhea, abdominal swelling, depression and other systemic symptoms; 5. All patients agreed to use condom contraceptives during the trial.
Exclusion criteria
Exclusion criteria: 1. Aged > 40 years; 2. BMI > 30 kg/m2; 3. Cervical Cytology examination abnormal need to be further diagnosis and treatment, patients is diagnosed with abnormal uterine bleeding. 4. Patients have a history of allergies to oral contraceptives, non-steroidal anti-inflammatory drugs, and light therapyantiphospholipid antibody syndrome.Contraindications for oral contraceptives and non-steroidal anti-inflammatory drugs, including hypertension, valvular disease or coronary heart disease, cerebrovascular disease, thrombophlebitis, thrombosis, abnormal liver function, including liver disease during pregnancy, severe renal insufficiency, diabetes, dyslipidemia, estrogen-dependent tumors, migraine, otosclerosis, thyroid dysfunction, depression, etc., And active or past peptic ulcers. 5. There are organic diseases requiring surgery, such as ovarian chocolate cyst, submucous uterine myoma, reproductive organ malformation, uterine cavity cervical adhesion and so on. 6. Patients with Endometriosis who underwent surgical treatment within 2 months of the baseline observation. Patients who have taken oral contraceptives in the past 2 months. 7. The diameter of chocolate cyst in ovary is more than 10 cm. 8. Or any disease, or the use of any drug, may hinder the conduct of research or interpretation of the results, can not be included in the study. 9. Patients who are pregnant, breast-feeding, or who wish to become pregnant within a predetermined period of treatment are also not included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;CMSS; | — |
Countries
China
Contacts
The First Hospital of Shanxi Medical University