gout
Conditions
Interventions
Control group:Placebo
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adult subjects with a diagnosis of gout and with TCM diagnosis of damp-heat obstruction syndrome; 2. Male and female patients aged 18-65 years with independent behavior ability; 3. Within 48 hours of acute attack, no other similar treatment was given within 14 days before the trial; 4. eGFR >= 30ml/min/1.73m2; 5. Patients must sign informed consent to enter clinical research.
Exclusion criteria
Exclusion criteria: 1) Female patients during pregnancy or lactation; 2) Patients are allergic to drug allergy of this subject or individual hypersensitivity; 3) The level of ALT was higher than 2 times normal; 4) Patients with serious primary diseases such as heart, liver, kidney, brain, endocrine system,hematopoietic system or mental illness; 5) Patients with severe joint deformity or even labor loss ; 6) Patients received the same treatment within 2 weeks before the trial; 7) Patients have the poor compliance to difficult to complete the clinical observer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale test;Evaluation of joint tenderness;Evaluation of joint swelling;Evaluation of joint activity;Ultrasound Imaging Score;blood uric acid;C-reactive protein;Erythrocyte sedimentation rate;interleukin-1ß;interleukin-6;interleukin-10;tumor necrosis factor-a; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome curative effect ratings;the total of urine uric acid in 24-hours; | — |
Countries
China
Contacts
Public ContactGAO Jian-Dong
TCM Institute of Kidney Disease, Shanghai university of Traditional Chinese Medicine
Outcome results
None listed