gout
Conditions
Interventions
A:The dosage of Allopurinol will increased gradually from 50 mg/d in the first four weeks,100 mg/d in the next four weeks, and to 200 mg/d to the end.
B:Allopurinol 200mg/d + Colchicine 0.5 mg/d.
C:Allopurinol 200mg/d
Sponsors
Anqing Hospital Affiliated to Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) All enrolled patients met the 1977 American college of rheumatology (ACR) gout classification criteria and/or the 2015 ACR gout classification criteria; 2) It is developed gout flares at least once in the previous year; 3) Serum uric acid >7.0mg/dl (420umol/L); 4) At least 1 month before entering the study, no uricate-lowering drugs were given; 5) Included in the study with written informed consent.
Exclusion criteria
Exclusion criteria: 1) Aged 1.5 mg/dL (133umol/L); 5) Those with severe comorbid conditions and those whom the researchers judged to be unsuitable candidates for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| uric acid; | — |
Countries
China
Contacts
Public ContactGuihong Wang
Department of Rheumatology, Anqing Hospital Affiliated to Anhui Medical University
Outcome results
None listed