Digestive System Disease
Conditions
Interventions
1:Sufentanil + propofol
2:Nabrephine 0.1mg/kg+ propofol
3:Nabrephine 0.2mg/kg+ propofol
4:Nabrephine 0.3mg/kg+ propofol
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years; 2. Body mass index (BMI):18~25 kg/m2; 3. American society of anesthesiologists (ASA) grade: I-II; 4. Patients who voluntarily underwent painless gastroenteroscopy and signed the informed consent;
Exclusion criteria
Exclusion criteria: 1. Hypertension > 180/110 mmHg or hypotension < 90/60 mmHg; 2. Long-term use of hormones and other immunosuppressive drugs; 3. Allergy to emulsions or opioids; 4. A history of obstructive sleep apnea dysfunction; 5. History of narcotic analgesic/sedative drug, psychotropic drug or alcohol abuse; 6. People with neuropsychiatric disorders who cannot communicate; 7. Patients with severe cardiac insufficiency, pulmonary insufficiency and other major organ dysfunction disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| satisfaction of patients;haemodynamics; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reaction of digestive endoscopy; | — |
Countries
China
Contacts
Public ContactTang Lili
The First Affiliated Hospital of Anhui Medical Univercity
Outcome results
None listed