functional dyspepsia with postprandial discomfort syndrome(Liver-stomach Disharmony Syndrome)
Conditions
Interventions
Experimental group:Chenxiang Qu, 9g, take orally, bid
Control group:Placebo, 9g, take orally, bid
Sponsors
Dongfang Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of functional dyspepsia postprandial discomfort syndrome; (2) Meet the diagnostic criteria of Liver-stomach Disharmony Syndrome; (3) Between 18 to 65 years old; (4) Voluntary participation and signing of informed consent
Exclusion criteria
Exclusion criteria: (1) Dyspepsia caused by organic diseases of digestive system, such as peptic ulcer, gastroesophageal reflux disease, erosive gastritis (grade 2 or more), atrophic gastritis, gastrointestinal cancer, gastrointestinal bleeding, hepatobiliary and pancreatic diseases, intestinal obstruction, inflammatory bowel disease, etc. B-mode ultrasonography, gastroscopy and laboratory examination showed abnormalities. There were significant evidence of gastrointestinal bleeding, gastrointestinal inflammation (ulcer, erosion, bleeding), including black stool, hematemesis, and palpable abdominal mass; (2) Hp positive; (3) Progressive dysphagia and swallowing pain, persistent vomiting and unconscious weight loss; (4) systemic diseases affecting digestive tract motility, such as diabetes mellitus, chronic renal insufficiency, connective tissue disease, neuropathy, etc.; (5) Abdominal surgery (except appendectomy and cesarean section); (6) Immune deficiency (such as leukemia, cancer patients, etc.) or the use of immunosuppressive agents or glucocorticoids in the past three months; (7) Severe cardiac insufficiency, liver and kidney function (ALT/AST is 1.5 times higher than the upper limit of normal value), endocrine system and hematopoietic system abnormalities, hematological examination indicates iron deficiency anemia; (8) Those with serious primary heart, brain, liver, lung, kidney, blood or serious diseases affecting their survival; (9) Disabled patients prescribed by law (blind, deaf, dumb, mental retardation, mental retardation, physical disability); (10) Pregnancy (positive pregnancy test for women of childbearing age) or lactation women, patients with recent fertility plans; (11) Allergic constitution, such as those who have allergic history to two or more medicines or food, and those who are allergic to the composition of this preparation; (12) Recent or ongoing clinical trials of other drugs, or drugs taken, may have an impact on the evaluation of the effectiveness of the tested drugs; (13) suspected or confirmed history of alcohol and drug abuse; (14) Severe anxiety and depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Upper abdominal distension, early satiety and belching severity score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM Syndrome Scoring;Evaluation of Western Medicine Symptoms;SF-36;Usage of Mosapride; | — |
Countries
China
Contacts
Public ContactJunxiang Li
Dongfang Hospital Affiliated to Beijing University of Chinese Medicine
Outcome results
None listed