melanoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. histological diagnosis of melanoma; 2. with unresectable multiple/disseminated liver metastasis; 3. failure of first-line systemic therapies or liver-directed therapies, or refuse these treatments; 4. performance score 0 or 1 on the Eastern Cooperative Oncology Group (ECOG) Performance Scale.
Exclusion criteria
Exclusion criteria: 1. receiving additional therapies except for these two treatment approaches before disease progression; 2. with other malignancies; 3. With active or a documented history of autoimmune disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective Response Rate;Progression-free Survival Time (PFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival Time (OS);Adverse Events; | — |
Countries
China
Contacts
Sun Yat-sen University Cancer Center