Pulmonary Hypertension
Conditions
Interventions
experimental group:An inflatable cuff was used for 3 cycles of lower extremity ischemia (to exceed the pressure of brachial artery systolic blood pressure (30mmHg) and 5 minutes of reperfusion.
control group:An inflatable cuff was used for 3 cycles of 5-minute pressure treatment (at 40mmHg pressure) and 5-minute pressure-free binding.
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Pulmonary hypertension patients undergoing pulmonary vascular intervention.
Exclusion criteria
Exclusion criteria: 1 Patients with occlusive vasculitis or arteritis involving lower extremity arteries; 2 Patients with venous thrombosis of lower extremities and 3 Patients who could not tolerate ischemic treatment of lower extremities (such as severe disability of lower extremities, recent stress fractures, severe burns and breakage of skin, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six-minute walk distance;pulmonary arterial systolic pressure;Interleukin-1 ß;Interleukin-6;Chest CT;Interleukin-8;Interleukin-10;active oxygen;prostacyclin;nitric oxide;adenosin;endothelin-1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Human fatty acid binding protein;nitrite;angiogenic growth factor;cyclic guanosine monophosphate;;Troponin-t;Creatine kinase isoenzyme;Tumor necrosis factor- a; | — |
Countries
China
Contacts
Public ContactYunshan Cao
Gansu Provincial People's Hospital
Outcome results
None listed