Experimental regimen of hydrocortisone, vitamin C and thiamine in the treatment of severe sepsis and septic shock

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024864

Enrollment

Unknown

Registered

2019-07-31

Start date

2019-09-01

Completion date

Unknown

Last updated

2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe sepsis and septic shock

Interventions

1:routine treatment

2:routine treatment +Vitamin C

3:routine treatment +Hydrocortisone

4:routine treatment +Vitamin B1

5:routine treatment+Vitamin C+Hydrocortisone+Vitamin B1

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with sepsis and septic shock.

Exclusion criteria

Exclusion criteria: Aged < 18 years, pregnancy, contraindication for using vitamin C and others.

Design outcomes

Primary

Measure	Time frame
28-day mortality;	—

Secondary

Measure	Time frame
28-day without pressor medication;28-day without mechanical ventilation;	—

Countries

China

Contacts

Public ContactZhao Heling

Hebei Gereral Hospital

zhheling@sina.com+86 13831129968

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026