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Evaluation of Intense Pulsed Light Combined With Anti-Demodex Treatment on Demodex Blepharitis and Related Dry Eye

Evaluation of Intense Pulsed Light Combined With Anti-Demodex Treatment on Demodex Blepharitis and Related Dry Eye

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024856
Enrollment
Unknown
Registered
2019-07-31
Start date
2019-07-29
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Demodex blepharitis

Interventions

1:IPL
2:Qiukui eye mask
3:IPL+ Qiukui eye mask
4:IPL+Tea tree oil eye mask

Sponsors

Hankou Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Patients who met the diagnosis of demodex blepharitis; 2. Light dry eye or light to moderate MGD; 3. Aged 18 to 50 years; 4. Symptom score: SPEED >= 6; 5. Schirmer test>=5 mm/min; 6. Changes in Meibomian glandular secretion; 7. Tear film breakup time <= 5s; 8. Subjects must sign informed consent, be willing to cooperate with treatment and follow-up, and voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: 1. Women during lactation or pregnancy; 2. Acute ocular inflammation or infection; 3. Eyelid margin has obvious scar or keratinization; 4. Received eye surgery or eyelid surgery within 6 months before enrollment; 5. Nerve palsy occurred in the treatment area within 6 months before enrollment; 6. Systemic disease including diabetes, autoimmune and infectious diseases; 7. Lacrimal duct embolization; 8. Precancerous skin cancer or pigmentation in the treatment area; 9. Had LASIK surgery within 12 months before enrollment; 10. Follow up observation less than 2 times after treatment; 11. The follow-up time exceeded the scheduled time by more than 1w; 12. Misdiagnosis found after the beginning of treatment (those meeting the exclusion criteria); 13. Receive ocular or systemic surgery during the study period; 14. New exclusion criteria occur or no data.

Design outcomes

Primary

MeasureTime frame
Number of Demodex;

Countries

China

Contacts

Public ContactQingyan Zeng

Hankou Aier Eye Hospital

zengqingyan1972@163.com+86 13971009610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026