Hypertension in children
Conditions
Interventions
VA deficiency Group 1:Health education
VA deficiency Group 2:VA intervention and health education
VA normal Group:health education
Sponsors
Childrens Hospital, Chongqing Medical University
Eligibility
Sex/Gender
All
Age
10 Years to 13 Years
Inclusion criteria
Inclusion criteria: 1. Aged 10-13 years; 2. Blood pressure level reached the diagnostic criteria of prehypertension and hypertension; 3. Did not take vitamin A supplements, beta carotene supplements, or vitamin A complex supplements for nearly 1 year; 4. Parents and children both signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Taking antihypertensive drugs; 2. Hypertension with obvious clinical symptoms; 3. Secondary hypertension; 4. Severe kidney, diabetes, cardiovascular disease, endocrine disease; 5. The guardian refused to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| systolic blood pressure;diastolic blood pressure;Lecithin retinol acyltransferase,LRAT;Retinoic Acid Receptors,RARs;Peroxidosome proliferators activate the receptor,PPARs;Renin angiotensin system,RAS;Retinyl ester,RE;Serum vitamin A;Ang II level;BMI;Waist;Hipline;Blood glucose;Creatinine;Uric Acid;Glycosylated hemoglobin;Insulin;Total cholesterol;Triglyceride;High-density lipoprotein;Low density lipoprotein;Zinc;Cuprum;Fe;Magnesium;Calcium;Serum vitamin D;Vitamin D Receptor;AO;LVDd;LVDs;carotid intima-media thickness (cIMT);RI;RI;the thickness of the wall of aortic sinus; | — |
Countries
China
Contacts
Public ContactXiaohua Liang
Childrens Hospital, Chongqing Medical University
Outcome results
None listed