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The effect of high frequency repetitive transcranial magnetic stimulation on heroin addiction and its brain mechanism

The effect of high frequency repetitive transcranial magnetic stimulation on heroin addiction and its brain mechanism

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024847
Enrollment
Unknown
Registered
2019-07-30
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heroin addiction

Interventions

Left DLPFC :10Hz rTMS Acts on Left DLPFC
Right DLPFC :10Hz rTMS Acts on Right DLPFC
Bilateral DLPFC :10Hz rTMS Acting on bilateral DLPFC respectively
Pseudo-stimulation group :nothing

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Aged from 30 to 60 years; 2 Long-term history of heroin addiction; 3 Subjects themselves sign informed consent.

Exclusion criteria

Exclusion criteria: 1 History of epilepsy, history of idiopathic epilepsy in first-degree relatives and use of epileptic drugs 2 Important organs, such as heart, lung, liver and kidney, suffer from hypofunction or failure; 3 Serious cognitive and communication barriers and unable to cooperate; 4 Wearing pacemakers, metal or electronic implants in the brain, or skull defects; 5 Direct injury of stimulation area. 6 Implants such as defibrillators, insulin pumps, drug treatment pumps, etc. 7 With neurological or psychiatric diseases and related medical history; 8 Drug detoxification treatment has been received in the past month.

Design outcomes

Primary

MeasureTime frame
VAS;

Secondary

MeasureTime frame
Functional magnetic resonance imaging (fMRI);

Countries

China

Contacts

Public ContactShen Ying

The First Affiliated Hospital of Nanjing Medical University

6326007@qq.com+86 13913913930

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026