Primary biliary cholangitis
Conditions
Interventions
Gold Standard:Liver biopsy pathology.
diagnostic 
model 
for 
fibrosis: 
AST/PLT 
value 
index 
(APRI 
model), 
Forns 
model, 
and 
based 
on 
Sponsors
Beijing You'an Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The diagnostic criteria of PBC are in line with the diagnostic guidelines for PBC in the 2015 Chinese Medical Association Liver Diseases Branch "Diagnosis and Treatment Consensus for Primary Biliary Cirrhosis". The gender is not limited, the age is 18 to 80 years old. The research plan was approved by the Ethics Committee of Beijing You'an Hospital, and the prospective patients signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1 Combined with chronic HBV, HCV, CMV, EBV infection or other causes of hepatitis and cirrhosis caused by alcohol, drugs; 2 Liver failure 3 combining primary liver cancer or liver metastases; 4 combined with fatty liver or severe cardiac insufficiency, organic kidney disease; 5 pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver biopsy pathological grading;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactYing Han
Beijing You'an Hospital, Capital Medical University
Outcome results
None listed