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Effect of different digestive tract reconstruction methods on postoperative digestive function in patients undergoing radical distal gastrectomy: a randomized, controlled, multicenter clinical study

Effect of different digestive tract reconstruction methods on postoperative digestive function in patients undergoing radical distal gastrectomy: a randomized, controlled, multicenter clinical study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024826
Enrollment
Unknown
Registered
2019-07-29
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Interventions

Billroth II:Billroth II gastrojejunostomy
Billroth II+ Brown:Billroth II gastrojejunostomy + Brown anastomosis
Roux-en-Y:Roux-en-Y gastrojejunostomy
uncut Roux-en-Y:uncut Roux-en-Y gastrojejunostomy

Sponsors

Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18 to 80 years (including 18 years), male or non-pregnant women; 2) Preoperative diagnosis of gastric cancer according to gastroscopy, tumor markers, upper abdominal imaging examination and feasible radical gastrectomy for distal gastroscopy; 3) Histopathological examination of patients with gastric cancer, postoperative pathological stage T2-4aN0-3M0.

Exclusion criteria

Exclusion criteria: 1) multiple primary cancers; 2) Laparoscopic exploration has a distant metastasis and cannot be treated surgically; 3) Patients with previous gastrectomy, gastric or small bowel surgery and any other form of gastrointestinal anastomosis; 4) severe mental disorders; 5) systemic corticosteroid application; 6) New adjuvant chemotherapy before surgery; 7) active bacterial infection or systemic fungal disease; 8) Unstable angina or myocardial infarction within 6 months before surgery; 9) unstable hypertension, poorly controlled or insulin-controlled diabetes; 10) Severe respiratory diseases require continuous oxygen therapy; 11) Patients undergoing emergency gastrectomy for gastric cancer-related complications (eg, perforation, bleeding, and obstruction); 12) Accompanying other digestive tract diseases that seriously affect digestive function (eg, severe constipation, duodenal stasis syndrome, etc.).

Design outcomes

Primary

MeasureTime frame
clinical symptoms and quality of life;Prognostic Nutrition Index;Degree of reflux gastritis;

Secondary

MeasureTime frame
Complications;

Countries

China

Contacts

Public ContactTianhang Luo

Shanghai Changhai Hospital

luotianhang78@126.com+86 13816977973

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026