Hypertension
Conditions
Interventions
Blood pressure controlled group:Peri-renal fat modification
Blood pressure uncontrolled group:Peri-renal fat modification
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-80 years old; 2. The minimun peri-renal fat volume of 8000mm3 is necessary of either side; 3. Patients provided written informed consent to participate in the trial; 4. Patients must meet one of blood pressure criteria of specific group below: (1) Blood pressure unctrolled group(BPU):? An office systolic blood pressure(OSBP) of between 150 mm Hg and 180 mm Hg and a diastolic blood pressure(ODBP) of 90 mm Hg or higher;? A mean 24 h ambulatory systolic blood pressure(AMBP) of between 135 mm Hg and 170 mm Hg.? Prescribed of not more than three antihypertensive drugs with stable doses for at least 6 weeks; (2) Blood pressure controlled group(BPC): An OSBP of between 120 and 140 mm Hg with an ODBP of between 70 and 90 mm Hg; ASBP was controlled less than 130 mmHg; More than one antihypertensive drugs of stable doses prescribed for at least 6 weeks.
Exclusion criteria
Exclusion criteria: 1. Patients with a secondary factor of hypertension; 2. Patients underwent other device based anti-hypertension therapy; 3. Patietns with other severe diseases(eg. end stage renal disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Office blood pressure;24h mean ambulatory blood pressure;Anti-hypertensive medicaitions;Blood chemistry;Angiotensin II;Blood aldosterone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Office heart rate;24h mean heart rate;Echocardiography;Renal and renal artery ultrasound;abdominal CT scan; | — |
Countries
China
Contacts
Public ContactXiangqing Kong
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed