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The mechanism of inhibition of bacterial biofilm in patients with pressure ulcer by negative pressure wound therapy combined with antibacterial dressing based on multimode control theory

The risk stratification and prevention strategies of pressure ulcers for critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024819
Enrollment
Unknown
Registered
2019-07-29
Start date
2019-01-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pressure ulcers

Interventions

experimental group:Negative pressure wound therapy combined with nano silver dressing
control group 1:Negative pressure wound therapy
control group 2:nano silver dressing

Sponsors

Jinling Hospital, Nanjing University medical school
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pressure ulcers in accordance with the definition of pressure ulcers III, IV; 2. Meet the biofilm 6 clinical diagnostic criteria; 3. Body temperature and blood sugar are normal; 4. Aged 18-70 years old; 5. Signed informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. tumor wound or cancerous wound; 2. large blood vessels exposed or bleeding wounds; 3. secondary systemic infection; 4. other systemic infections requiring systemic use of antibiotics; 5. unprovoked fistula; 6. untreated osteomyelitis

Design outcomes

Primary

MeasureTime frame
Bacterial biofilm structure and quantitative changes in wound;—

Secondary

MeasureTime frame
Reduction rate of wound volume;Pressure ulcer healing scale;Change of wound temperature, acidity and alkalinity and composition of infiltration fluid;Bacterial culture;Wound healing rate;Wound healing time;—

Countries

China

Contacts

Public ContactJiang Qixia

Jinling Hospital, Nanjing University medical school

jiangqixia1963@163.com+86 18900672707

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026