Interstitial lung disease
Conditions
Interventions
Observational group:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged over 18 years; 2. Diagnosis meets the diagnostic criteria for IPF, CTD-ILD, or CTD; 3. Suspected cases must be confirmed by a multidisciplinary team within the research group; 4. Expected survival time is more than 1 year.
Exclusion criteria
Exclusion criteria: 1. Comorbidities that may significantly affect the prognosis of CTD-ILD/IPF, such as pneumoconiosis, silicosis, or malignant tumors; 2. Pregnant or breastfeeding women; 3. Participants who are unable to comply with the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of PFT;Total exacerbations;Blood tests (Complete Blood Count, Biochemistry, C-Reactive Protein, Erythrocyte Sedimentation Rate, Procalcitonin, Interleukin-6, Immune-related tests, Tumor Necrosis Factor-alpha);Bronchoalveolar Lavage Fluid (BALF) Cytomics and Genomics;Cryobiopsy Related Information (Surgical Procedure, Pathology Results of the Specimen, Follow-up Information for Three Days Post-Procedure);Dyspnea Scales and Classification (mMRC Questionnaire, Borg Dyspnea Scale);Cough Assessment (Cough Symptom Score, Cough VAS Score);King's Brief Interstitial Lung Disease questionnaire;Six-Minute Walk Test;Exhaled Nitric Oxide, FeNO; | — |
Secondary
| Measure | Time frame |
|---|---|
| Survival time;Symptom evaluation;forms of 'acute exacerbation';Grades of HRCT;The MOS item short from health survey;Changes of inflammation markers;Pulmonary artery hypertension;BMI; | — |
Countries
China
Contacts
Public ContactFengming Luo
West China Hospital, Sichuan University
Outcome results
None listed