Effects of different doses of dexmedetomidine on resuscitation and postoperative adverse reactions in patients undergoing laparoscopic cholecystectomy

Effects of different doses of dexmedetomidine on resuscitation and postoperative adverse events in patients undergoing laparoscopic cholecystectomy: a randomized double-blind controlled prospective trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024801

Enrollment

Unknown

Registered

2019-07-28

Start date

2019-07-18

Completion date

Unknown

Last updated

2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic cholecystectomy

Interventions

The control group:no intervention

D1:Dexmedetomidine 0.4ug/kg was injected 10 minutes before induction of anesthesia

D2:Dexmedetomidine 0.6ug/kg was injected 10 minutes before induction of anesthesia

D3:Dexmedetomidine 0.8ug/kg was injected 10 minutes before induction of anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Adult patients under 50 years of age; 2.ASA 1-2; 3.18.5< BIM < 28.

Exclusion criteria

Exclusion criteria: 1.Contraindication to narcotic drugs; 2.Allergic to dexmedetomidine; 3.History of asthma; 4.History of psychosis or psychotropic drug use; 5.Cognitive dysfunction.

Design outcomes

Primary

Measure	Time frame
Degree of cough during recovery;Sedation-Agitation Scale;Ramsay Scale;Visual Analogue Scale;Postoperative nausea and vomiting;	—

Countries

China

Contacts

Public ContactFangjun Wang

North Sichuan Medical College

wfjlxy006@126.com+86 13458253172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 23, 2026