breast cancer
Conditions
Interventions
Preemptive Analgesia Group :Preoperative application of flurbiprofen
Postoperative analgesia group :Useing flurbiprofen before the end of operation
control group :Routine anaesthesia
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years; 2. Female; 3. BMI 18-30 kg/m2; 4. ASA I-III; 5. Patients volunteer to participate in the trial and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous surgical history of breast diseases, including mass excision and biopsy, excluding puncture; 2. Simultaneous or planned breast prosthesis reconstruction and bilateral breast surgery; 3. Intraoperative pathological returns as benign or insufficient evidence of malignant; 4. Diagnosis of gastrointestinal ulcer by endoscopy; 5. Uesing durgs those affecting platelet or coagulation and fibrinolysis systems within two weeks; 6. Patients with aspirin asthma history; 7. Patients currently using enoxacin, lomefloxacin and Norfloxacin; 8. History of long-term use of opioids and NSAIDS drugs; 9. HAD score more than 7; 10. Complicated with severe cardiovascular and cerebrovascular diseases, liver, kidney and blood system dysfunction; 11. Drug allergies to anesthesia and analgesia involved in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ASA score; | — |
Countries
China
Contacts
Public ContactXing Zeyu
Anesthesiology Department, Cancer Hospital Chinese Academy of Medical Sciences
Outcome results
None listed