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Clinical features and abnormal functional network of epilepsy with amygdala enlargement

Clinical features and abnormal functional network of epilepsy with amygdala enlargement

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024763
Enrollment
Unknown
Registered
2019-07-26
Start date
2019-08-15
Completion date
Unknown
Last updated
2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

response versus no response:drug treatment

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. According to the diagnostic criteria of the international alliance against epilepsy in 2005 and 2014: 1) at least 2 non-induced (or reflexive) episodes with an interval of more than 24 hours; 2) diagnosis of a certain epilepsy syndrome; 2. Rule out possible intracranial infection, autoimmune diseases and other inflammatory diseases; 3. Patients or their families have the ability to record epilepsy diary; 4. Patients can tolerate and are willing to cooperate in completing the examination required by the study, and patients and their families sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Structural integrity of amygdala was damaged, such as amygdala softening lesions and glial hyperplasia caused by trauma or vascular malformation; 2. Imaging highly suspected neoplastic lesions: accompanied by high signals of calcification, cystic degeneration and clear boundary; 3. The patient has progressive lesions, or the cognitive and general conditions are difficult to complete the examination required by the study; 4. Patients or family members cannot cooperate or refuse to cooperate.

Design outcomes

Primary

MeasureTime frame
Video-Electroencephalography;Brain MRI;Cognitive scale;Emotional scale;Event dependent potential;

Countries

China

Contacts

Public ContactYouting Lin

Shandong Provincial Hospital

linyouting@foxmail.com+86 15806415900

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026