Obesity
Conditions
Interventions
Sponsors
Department of Endocrinology and Metabolism, Zhujiang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Men and women aged 18-65 years old; 2. The definition of obesity in Chinese adults is based on the "2003 Guidance on Prevention and Control of Obesity in Chinese Adults": 1) BMI 24 to 28 kg/m2 for overweight; 2) BMI>=28kg/m2 for obesity; 3. Moderate weight changes and exercises over the last 30 days (less than 60 minutes of exercise every week); 4. Patient and family voluntarily participate in and cooperate with and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant women or women who are planning to be pregnant during the study, women who are currently in lactating, or who have not received highly effective, medical-approved birth control methods; 2. Combined with malignant tumors, multiple organ dysfunction and other chronic wasting diseases; 3. Severe hypertension,severe cardiovascular and cerebrovascular disease and severe liver/renal dysfunction; 4. Concurrent C. difficile infection or other known infections; 5. Subjects who had a history of FMT; 6. Diarrhea caused by other reasons, including but not limited tube feeding and drug; 7. Those who undergone gastrointestinal surgery (except for appendectomy) or gallbladder surgery; 8. Severe food allergy; 9. Patients with severe neurological, mental or mental disease; 10. Stomach inhalation within 90 days; 11. Patients who take oral probiotics, prebiotics, antibiotics or proton pump inhibitors (PPIs) within 2 weeks or for any reason,during the study period,take antibiotics, or need toal probiotics, opioids, loperamide or diphenoxylate; 12. Patients who have taken or need to take immunosuppressive agents or hormones during use or during the study; 13. Those who take weight-loss drugs within 90 days or who plan to use GLP-1 receptor agonists, or any weight-loss drugs, or participate in a weight loss study or weight loss program during the study; 14. Those who are participating or participating in other clinical trials within 3 months; 15. Patients with severe diabetic complications; 16. Other endocrine diseases expect for type 1 and type 2 diabetes, such as thyroid and special type diabetes; 17. Patients who are judged by the current researcher that they are inappropriate or impossible to cooperate and complete the entire intervention and observer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Index of glucose metabolism;Serum Lipid;Intestinal flora;body fat;adverse events; | — |
Countries
China
Contacts
Public ContactHong Chen
Department of Endocrinology and Metabolism, Zhujiang Hospital, Southern Medical University
Outcome results
None listed