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Effects of intraoperative lidocaine infusion combined with postoperative intravenous analgesia on serum interleukin and postoperative chronic pain in patients with lung cancer.

Effects of intraoperative lidocaine infusion combined with postoperative intravenous analgesia on serum interleukin and postoperative chronic pain in patients with lung cancer:A randomized, controlled, double-blind prospective trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900024759
Enrollment
Unknown
Registered
2019-07-26
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Experimental group:Lidocaine induction, intraoperative pumping and postoperative analgesia
Control group:Same volume infusion as lidocaine group

Sponsors

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. aged 18-70 years old; 2. ASA I or II; 3. Thoracoscopic lung cancer resection; 4. signed informed consent.

Exclusion criteria

Exclusion criteria: 1. changes in surgical methods;(including wedge lobectomy only or intraoperative conversion to thoracotomy); 2. congestive heart failure; 3. severe arrhythmia; 4. preexcitation syndrome; 5. renal failure and liver failure; 6. allergic to local anesthetic drugs.

Design outcomes

Primary

MeasureTime frame
Interleukin-1beta;Interleukin-6;Interleukin-8;Postoperative chronic pain;—

Countries

China

Contacts

Public ContactWangning Shangguan

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University

sgwning@163.com+86 13587637891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026