dentomaxillofacial deformities
Conditions
Interventions
group A:increase the dose of anesthetic
Sponsors
The Third Affiliated Hospital of the Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for orthognathic surgery in the department of Oral and maxillofacial surgery of The Third Affiliated Hospital of the Air Force Military Medical University; 2. Proposed surgery: Maxillary LEFORTI osteotomy + mandibular sagittal split surgery + genioplasty (with or without); 3. Aged 18 to 45 years old.
Exclusion criteria
Exclusion criteria: 1. Refused to sign the informed consent; 2. Preoperative SBP=140mmHg and/or DBP=90mmHg; Preoperative SBP=90mmHg and/or DBP=60mmHg; 3. patients with abnormal ECG; 4. patients with abnormal blood routine examination; 5. patients with abnormal coagulation system; 6. patients with abnormal renal function; 7. patients with abnormal Chest X-ray; 8. patients with ASA=II; 9. BMI=27kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SIRS with brain dysfunction (stroke or postoperative delirium) during 24 hours after surgery;SIRS with renal dysfunction (AKIN: level? or above)during 24 hours after surgery;SIRS with with cardiac dysfunction (arrhythmia or myocardial ischemia or infarction) during 24 hours after surgery;SIRS with pulmonary dysfunction (hypoxemia or pneumonia) during 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of SIRS during 24 hours after surgery;Incidence of brain dysfunction (stroke or postoperative delirium) during 24 hours after surgery;Incidence of acute kidney injury (AKIN: level?or above) during 24 hours after surgery;Incidence of cardiac dysfunction (arrhythmia, myocardial ischemia or infarction) during 24 hours after surgery;Incidence of pulmonary dysfunction (hypoxemia or pneumonia) during 24 hours after surgery;PSI and SR during the operation;HR and BP during the operation;Infusion volume, blood transfusion volume, blood loss volume, urine volume;dose of propofol, sevoflurane,remifentanil and nicardipine;time of controlled hypotension and time of operation;Incidence of PONV during 24 hours after surgery;Time of tracheal tube removal;Time of waking up to steward 6;The time when MAP increased to 65mmHg after the cessation of controlled hypotension;Incidence of postoperative infection;LOS(length of stay); | — |
Countries
China
Contacts
Public ContactZhang Hui
The Third Affiliated Hospital of the Air Force Military Medical University
Outcome results
None listed