The program of haploidentical allogeneic hematopoietic stem cell transplantation for children with SAA

Clinical study of haploidentical allogeneic hematopoietic stem cell transplantation for children in severe aplastic anemia(SAA) patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900024745

Enrollment

Unknown

Registered

2019-07-26

Start date

2019-10-01

Completion date

Unknown

Last updated

2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe aplastic anemia(SAA)

Interventions

FLU+ATG group:FLU+ATG

PTCy group:PTCy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Severe aplastic anemia(SAA)patients without matched related donor(MRD)or meet the transplantation needs of the unrelated donor (URD), Meet one of the following criteria: 1. All patients with severe aplastic anemia (SAA) who have experienced treatment failure to immunotherapy (IST); 2. SAA patients whose family members asked for transplantation as the preferred treatment.

Exclusion criteria

Exclusion criteria: Severe infection causes migration process there is a danger of life SAA patients

Design outcomes

Primary

Measure	Time frame
event-free survival ,EFS;overall survival,OS;	—

Secondary

Measure	Time frame
The implantation time of Granulocyte;The implantation time of platelet;the incidence of implation;chimerism;GVHD;The mortality of Transplant;??????;Pathogens associated with Posttransplant infection;The level of Cytokine;Genetic test;	—

Countries

China

Contacts

Public ContactJiang Hua

Guangzhou Women and Children's Medical Center

jiang_hua18@sina.cn+86 13533330985

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026