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A historical cohort study for comparison of Allografts mixed with Platelet-Rich Plasma versus Autografts for long bone nonunion: retrospective analysis based on case records

A historical cohort study for comparison of Allografts mixed with Platelet-Rich Plasma versus Autografts for long bone nonunion: retrospective analysis based on case records

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024740
Enrollment
Unknown
Registered
2019-07-26
Start date
2019-09-01
Completion date
Unknown
Last updated
2022-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

long bone nonunion

Interventions

Group 1:allograft mixed with platelet-rich plasma (PRP)
control group:Autogenous bone graft

Sponsors

Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years old; 2. Patients with atrophic nonunion of long bone and bone graft; 3. Follow-up for at least 9 months already; 4. patient demographic frature and medical history data were completed; 5. X-ray and CT scan were done before grafting and X-ray were done after grafting.

Exclusion criteria

Exclusion criteria: 1. primary open fracture; 2. hypertrophic nonunion; 3. pathological fracture (tumor or metabolic bone disease); 4. rheumatism; 5. Infectious nonunion; 6. immature bones; 7. blood system diseases; 8. radiation therapy; 9. chemotherapy; 10. chronic treatment of steroids; 11. pregnancy.

Design outcomes

Primary

MeasureTime frame
Healing time of nonunion;—

Secondary

MeasureTime frame
healing rate of nonunion;—

Countries

China

Contacts

Public ContactWu Shenghui

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

wushenghui@sjtu.edu.cn+86 18250466796

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026