Hypersalivation
Conditions
Interventions
Group A:Botulinum Toxin A of 60 Units
Group B:Botulinum Toxin A of 80 Units
Sponsors
Third Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
4 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1) Children whose salivation accords with the teacher's salivation classification method reaching grade III-V; 2) Outpatient and hospitalized children with cerebral palsy, mental retardation and post-traumatic salivation in the Third Affiliated Hospital of Zhengzhou University; 3) Children over 4 years old; 4) After the informed consent of the patient's family members and the signing of written opinions, they were included in the study.
Exclusion criteria
Exclusion criteria: 1) Patients with systemic neuromuscular disease; 2) Applying aminoglycoside antibiotics and other drugs that interfere with neuromuscular transmission in the near future; 3) Fever or infectious disease in active stage or injection site infection; 4) Patients with masseter weakness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| teacher drooling sizing;Weighing method;The drool scale; | — |
Countries
China
Contacts
Public ContactDengna Zhu
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed