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A research for IgE-independent allergic asthma mediated by MRGPRX2

A research for IgE-independent allergic asthma mediated by MRGPRX2

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024672
Enrollment
Unknown
Registered
2019-07-20
Start date
2019-07-20
Completion date
Unknown
Last updated
2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic asthma

Interventions

Gold Standard:(1) When enrolling, ask and record the patient's demographic data, current medical history, allergic history, past history, family history and other detailed disease data. (2) Inclusion
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Sponsors

Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) The age range is 6-80 years old; (2) The disease is diagnosed as allergic asthma; (3) Those who voluntarily participate in the project and can perform as required; (4) Those who have signed the informed consent form and are able to complete it as required. Control group: (1) Healthy physical examination population; (3) Family genetic history of non-allergic asthma; (4) There is no disease in the near future.

Exclusion criteria

Exclusion criteria: (1) Patients with allergic asthma who have other diseases; (2) Patients with clear indications of acute infection; (3) Patients who cannot cooperate or cannot adhere to treatment and predict poor compliance; (4) pregnant women and lactating women; (5) The patient is also participating in other clinical trial studies.

Design outcomes

Primary

MeasureTime frame
Serum IgE;Serum substance P;Peripheral blood MRGPRX2 gene copy number;Peripheral blood MRGPRX2 receptor mRNA expression level and protein expression level;

Countries

China

Contacts

Public ContactLangchong He

Xi'an Jiaotong University

helc@mail.xjtu.edu.cn+86 029 82655392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026