contrast-induced acute kidney injury
Conditions
Interventions
Gold Standard:creatinine increased 44.2 µmol/L or more, and higher 25% than the basic level at 48h to 72h after application of iodine contrast agent
and 
MicroRNAs 
Sponsors
Department of Cardiology, Zhongda Hospital of Southeast University Medical School
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Volunteered to participate in this trial and signed informed consent; (2) Aged more than 18 Years; (3) Suspected as Coronary heart disease and Planned to execute Coronary angiography.
Exclusion criteria
Exclusion criteria: (1) Hypersensitivity to iodine-containing compounds; (2) CKD stages 5 (eGFR < 30ml/min per 1.73m2) or under Maintenance hemodialysis; (3) acute ST-segment elevation myocardial infarction (STEMI); (4) NYHA class IV or hemodynamic instability; (5) Take CT, MRI and other examinations with contrast agents during the two weeks before study; take radiographic examination of other contrast agents during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome Measures:The incedence of CI-AKI;serum MicroRNAs and LncRNAs;urinary MicroRNAs and LncRNAs; | — |
Countries
China
Contacts
Public ContactYan Gaoliang
Zhongda Hospital of Southeast University
Outcome results
None listed