Clinical significance of Bcl-2/adenovirus E1B 19kDa interacting protein 3 in patients with hand-foot-mouth disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900024647

Enrollment

Unknown

Registered

2019-07-19

Start date

2019-07-30

Completion date

Unknown

Last updated

2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hand-foot-and-mouth disease

Interventions

Critical group versus severe group versus common group:Nil

Eligibility

Sex/Gender

All

Age

0.5 Years to 6 Years

Inclusion criteria

Inclusion criteria: The inclusion and grouping criteria were formulated according to Chinese guidelines for the diagnosis and treatment of HFMD (2018 edition). The inclusion criteria included children with HFMD who were between the ages of 6 months and 6 years, and the disease course was between 2 and 5 days.

Exclusion criteria

Exclusion criteria: With history of brain trauma, epilepsy, brain dysplasia concurrent pneumonia, and concurrent enteritis

Design outcomes

Primary

Measure	Time frame
serum BNIP3;CSF BNIP3;	—

Secondary

Measure	Time frame
serum NSE;serum S100B protein;	—

Countries

China

Contacts

Public ContactZhu Lei

Xuzhou Children's Hospital of Xuzhou Medical University

xuzhouzhulei317@163.com+86 13685134366

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026