Ambispective Cohort Study of Chronic Airway Disease in Chinese Guangdong

Conditions

Chronic Obstructive Pulmonary Disease

Lu L, Tang G, Wan Q, Wu F, Deng Z, Peng J, Dai C, Zhou K, Wu X, Li S, Cai G, Huang S, Lin J, Yu S, Huang Y, Yang C, Chen S, Ran P, Zhou Y.

2026-04-16

10.1136/bmjresp-2025-003918

Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in China.

Zhou Y, Wu F, Deng Z, Wang Z, Tian H, Huang P, Zheng Y, Yang H, Zhao N, Dai C, Yang C, Yu S, Tian J, Cui J, Liu S, Wang D, Wang X, Lu J, Zhong N, Ran P.

2025-04-283 citations

10.1186/s12931-025-03244-3

Associations of small airway dysfunction assessed by impulse oscillometry with lung function decline and exacerbations in participants with chronic obstructive pulmonary disease: A prospective cohort study in China.

Lu L, Wu F, Tang G, Wan Q, Deng Z, Peng J, Dai C, Zhou K, Wu X, Yu S, Huang Y, Yang C, Chen S, Ran P, Zhou Y.

2025-03-314 citations

10.1016/j.rmed.2025.108075

Association of Exercise Tolerance with Respiratory Health Outcomes in Mild-to-Moderate Chronic Obstructive Pulmonary Disease

Qi Wan, Zhishan Deng, Fan Wu, Youlan Zheng, Huajing Yang et al. (22 authors)

Annals of the American Thoracic Society2024-11-252 citations

10.1513/annalsats.202404-408oc

New Classifications of COPD Severity Based on Impulse Oscillometry: A SAIO Grade Base on ECOPD Cohort in China.

Lu L, Wan Q, Tang G, Wu F, Deng Z, Peng J, Dai C, Zhou K, Wu X, Yu S, Huang Y, Yang C, Chen S, Ran P, Zhou Y.

2024-10-22

10.1016/j.arbres.2024.10.005

Clinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study.

Lu L, Wu F, Peng J, Wu X, Hou X, Zheng Y, Yang H, Deng Z, Dai C, Zhao N, Zhou K, Wan Q, Tang G, Cui J, Yu S, Luo X, Yang C, Chen S, Ran P, Zhou Y.

2024-03-303 citations

10.1186/s12931-024-02765-7

The association between small airway dysfunction and aging: a cross-sectional analysis from the ECOPD cohort.

Dai C, Wu F, Wang Z, Peng J, Yang H, Zheng Y, Lu L, Zhao N, Deng Z, Xiao S, Wen X, Xu J, Huang P, Zhou K, Wu X, Zhou Y, Ran P.

2022-09-046 citations

10.1186/s12931-022-02148-w

Rationale and design of the Early Chronic Obstructive Pulmonary Disease (ECOPD) study in Guangdong, China: a prospective observational cohort study

Fan Wu, Yumin Zhou, Jieqi Peng, Zhishan Deng, Xiang Wen et al. (15 authors)

Journal of Thoracic Disease2021-12-0148 citations

10.21037/jtd-21-1379

Clinical characteristics of and risk factors for small airway dysfunction detected by impulse oscillometry.

Peng J, Wu F, Tian H, Yang H, Zheng Y, Deng Z, Wang Z, Xiao S, Wen X, Huang P, Lu L, Dai C, Zhao N, Huang S, Ran P, Zhou Y.

2021-11-1118 citations

10.1016/j.rmed.2021.106681

Interventions

Population-based Ambispective Cohort:NA

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Local residents aged 40-80 years in Guangdong; (2) Consent to participate and sign informed consent.

Exclusion criteria

Exclusion criteria: With serious diseases

Design outcomes

Primary

Measure	Time frame
Completion rate of cohort establishment;Completion rate of evaluation of clinical indicators;Completion rate of blood sample collection;Data integrity rate;loss to follow up rate;	—

Countries

China

Contacts

Public ContactPixin Ran

Guangzhou Medical University

pxran@gzhmu.edu.cn+86 13922765811

Outcome results

None listed