Diabetic retinopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Control group: A total of 37 patients (37 eyes) with normal eye examination results at the ophthalmology outpatient department of the Nanjing Medical University Affiliated Wuxi Second Hospital were included as controls. The right eye data were collected. The inclusion criteria were as follows: 1. BCVA of >= 0.8, with normal visual field and intraocular pressure; and 2. no history of diabetes. DR group: A total of 37 patients with NPDR who were treated with PRP in the ophthalmology clinic were selected as the DR group. According to the ETDRS Research Group, all patients were included based on the fundus examination and fluorescein fundus angiography (FFA) findings indicating severe NPDR, and thus requiring PRP.
Exclusion criteria
Exclusion criteria: Control group: 1. refractive media turbidity affecting the sharpness of scanned images; 2. history of ophthalmic surgery or ocular trauma; 3. eye disease and family history of glaucoma, retinal detachment, or macular degeneration; 4. history of other systemic disease. DR group: 1. other eye diseases (including age-related macular degeneration, hypertensive retinopathy, retinal detachment, retinal vascular disease, and uveitis); 2. history of intraocular surgery (including vitrectomy, scleral buckling, and glaucoma surgery); 3. apparent cataracts, vitreous hemorrhage, and macular edema caused by poor scanning quality (scan quality [SQ] of <5); 4. history of ocular treatment (including intravitreal or intramuscular injection of triamcinolone acetonide or anti-vascular endothelial growth factor, or focal or grid laser photocoagulation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vessel density;BCVA; | — |
Countries
China
Contacts
Wuxi Second Hospital affiliated to Nanjing Medical University