Tumor-related peripheral neuropathy
Conditions
Interventions
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Malignant tumor diagnosed by histopathology; (2) >= Grade1peripheral neurotoxicity (including paresthesia and neuropathic pain)afterchemotherapy with oxaliplatin (with or without other chemotherapy regimen), and no planned chemotherapy within 1 month after enrollment; (3) KPS >= 70, PS score <= 2; (4) Male or female, aged 18 to 80 years; (5) No mental disorders, normal language ability and selfjudgement onpain, general conditionsand quality of life; (6) Understand this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Critically ill patients with severe pain elsewhere. (2) Symptomaticbrain metastasis or other neurological symptom due to metastasis. (3) Neuropathy caused by electrolyte disturbance and other severe systemic diseases, such as diabetes, cervical spondylosis, disc compression. (4) Skin lesionsof hand or foot. (5) History of allergic reaction to external medication. (6) History of drug abuse or addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of peripheral neurotoxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| The degree of pain;onset time;Quality of life evaluation;Observation of TCM syndrome;Safety;Correlation analysis of cumulative dose and adverse reactions;Serum NGF level; | — |
Countries
China
Contacts
Public ContactShi Jun
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed