The effect of ketamine-dexmedetomidine on the incidence of postoperative delirium in pediatric patients after neurological surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024570

Enrollment

Unknown

Registered

2019-07-17

Start date

2019-07-15

Completion date

Unknown

Last updated

2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

intervention group:ketamine and dexmedetomidine

Control group:saline

Eligibility

Sex/Gender

All

Age

2 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1) Pediatric patients of elective neurological surgery in general anesthesia; 2) Expected surgery duration more than 2 hours; 3) Age 2-16 years.

Exclusion criteria

Exclusion criteria: 1) refused to participate; 2) poor invision and/or hearing impeding assessment of delirium; 3) poor cognitive function impeding assessment of delirium; 4) ASA>=4.

Design outcomes

Primary

Measure	Time frame
incidence of postoperative delirium within 5 days;	—

Secondary

Measure	Time frame
incidence of emergence delirium;postoperative 30-day compliations and mortality;postoperative hospital length of stay;expense during hospital stay;biological indicator: preoperative and postoperative inflammatory factor and neurological injury markers;	—

Countries

China

Contacts

Public ContactMu Dongliang

Peking University First Hospital

mudongliang@icloud.com+86 010-83573218

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026