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Application of quantitative analysis of contrast-enhanced ultrasound in early diagnosis of small hepatocellular carcinoma in patients with liver cirrhosis

Application of quantitative analysis of contrast-enhanced ultrasound in early diagnosis of small hepatocellular carcinoma in patients with liver cirrhosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900024556
Enrollment
Unknown
Registered
2019-07-16
Start date
2019-08-01
Completion date
Unknown
Last updated
2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Small Hepatocellular Carcinoma

Interventions

Gold Standard:Pathological biopsy results
Index test:Quantitative&#32
parameters&#32
of&#32
contrast-enhanced&#32
ultrasound:TIC,&#32
PI,&#32
AUWI,&#32
AUWO,&#32
TPI&#32
and&#32
SWI.

Sponsors

Beijing Youan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Small nodules and suspicious HCC were found in hepatic parenchyma by imaging examination, and the diameter of the nodule range from 1.0 cm to 3.0 cm; 2. Before the CEUS examination, no interventional or chemotherapy treatment was received; 3. There was no allergic reaction to SonoVue; 4. Willing to receive liver biopsy or surgical treatment; 5. Volunteer to participate in the experiment and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Diffuse primary hepatocellular carcinoma; 2. The focus is close to the heart, which is not good for CEUS image observers.

Design outcomes

Primary

MeasureTime frame
Peak intensity;TIC;—

Countries

China

Contacts

Public ContactMENG FANKUN

Beijing Youan Hospital, Capital Medical University

mengfankun818@126.com+86 13811565771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026