Drug Addiction
Conditions
Interventions
Short interval group:Paired associated stimulation-10ms
Long-interval group:Paired associated stimulation-100ms
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1 Healthy; 2 No contraindication to transcranial magnetic stimulation; 3 aged 18-60 years; 4 Non-literate, at the third grade or above in primary school, able to read and understand basic sentences; 5 The drug abuse time is more than one year, the frequency of use is greater than one week, and the monthly use is greater than 1 gram; 6 Willing to participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1 There are contraindications to transcranial magnetic (TMS) treatment, such as head trauma, history of epilepsy, and metal implants in the body; 2 Other mental illnesses other than substance-related and addictive disorders (e.g., depression, bipolar disorder, schizophrenia); 3 a serious physical illness or a major organ disease; 4 Intelligence impairment (IQ<90) or the number of years of schooling is too low.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Craving;EEG signal; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropsychological (e.g., depression, anxiety, craving, sleep, impulsivity, suicide attitude, obsessive symptom, sensation seeking);Cognitive functions (e.g., inhibit control, working memory, decision making, reinforcement learning, emotional recognition); | — |
Countries
China
Contacts
Public ContactTifei Yuan
Shanghai Mental Health Center
Outcome results
None listed