Effect of Different Concentration of Esmolol on Adjuvant Analgesia and Hemodynamics in Patients Undergoing Colectomy

Effect of Different Concentration of Esmolol on Adjuvant Analgesia and Hemodynamics in Patients Undergoing Colectomy: A Prospective, Randomized Controlled Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900024538

Enrollment

Unknown

Registered

2019-07-15

Start date

2019-08-01

Completion date

Unknown

Last updated

2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Stress and Postoperative Pain

Interventions

Group C:Normal saline

Group E1:low dose of Esmolol

Group E2:High dose of Esmolol

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients undergoing elective colectomy with ASA I-III, aged 20-70 years.

Exclusion criteria

Exclusion criteria: 1. Patients with bradycardia and atrioventricular block; 2. Patients with hypotension; 3. Patients with bronchial asthma and severe chronic obstructive pulmonary disease; 4. Patients with severe heart, liver and kidney dysfunction; 5. Disagree with or fail to cooperate test.

Design outcomes

Primary

Measure	Time frame
Blood Pressure;Heart Rate;Postoperative pain score;Dosage of Opioids;	—

Secondary

Measure	Time frame
age;Sex;Intraoperative fluid intake;	—

Countries

China

Contacts

Public ContactSong Fuxi

The Second Hospital of Shandong University

songfuxi@sdu.edu.cn+86 13573756464

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026