Osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 40-70 years; 2. Voluntary participation in lumbar DXA, QCT and MRI examinations.
Exclusion criteria
Exclusion criteria: 1. Abnormal bone metabolism, such as hyperparathyroid, diabetes, Cushing's syndrome, renal bone malnutrition, etc.; 2. Take drugs that affect bone metabolism, such as corticosteroids, calcitonin, vitamin D, bisphosphonates, etc.; 3. History of malignant tumor after radiation therapy or chemotherapy; 4. Stay in bed for more than 1 week; 5. Severe depression, schizophrenia and other mental diseases or long-term use of antipsychotics; 6. People with claustrophobia, pacemaker implantation or other causes who can not undergo an MRI examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone Mineral Density (BMD);Bone Mineral Density (3D-BMD);Fat fraction;Parameters of blood perfusion;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Shanghai Tenth People's Hospital