oral disease
Conditions
Interventions
experimental group:received oral etoricoxib 60mg before surgery
control group:oral placebo before surgery
Positive control group:Oral non-steroidal anti-inflammatory analgesics before surgery
Sponsors
Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. aged at least 18 years; 2. X - ray showed horizontal impacted teeth; 3. the patient consented to the trial; 4. no allergic history of steroidal drugs; 5. no analgesic and anti-inflammatory drug before surgery.
Exclusion criteria
Exclusion criteria: 1. pregnant or nursing; 2. with other serious diseases include liver, kidney, and cardiovascular disease; 3. contraindicated the use of Cox-2 inhibitors 4. ulcers or bleeding in the digestive tract; 5. unable to express subjective discomfort symptoms; 6. caries or periapical periodontitis, periodontal disease with adjacent teeth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the intensity of pain;Swallowing pain;Open mouth pain;Wound pain;Quality of life score;total analgesic consumption in 7 days;swelling;trismus; | — |
Secondary
| Measure | Time frame |
|---|---|
| time for the first analgesic rescue medication;total analgesic consumption in 24 hours; | — |
Countries
China
Contacts
Public ContactXie Long
Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University
Outcome results
None listed